$ZLTQ is one of biggest losers #stocks today. read more:

ZELTIQ Aesthetics, Inc. (symbol: ZLTQ) was one of the worst losers of the
trading day today (2016-03-01), losing -9.64%. The number of shares that
changed hands was 3,860,383, or about 4 times the average daily volume in
the stock.
The closing price was $20.81, amounting to a market cap of $812,110,000,
about -45.93% off the highest price in the last 12 months. The stock has
been trading at a range between $18.41 and $38.49.
ZLTQ is in the Biotechnology: Electromedical & Electrotherapeutic Apparatus
industry, part of the Health Care sector. It first went public in 2011.
Looking at its valuation, the stock is now trading at 346.83 times earnings.