$UTHR is one of biggest losers #stocks today. read more:

United Therapeutics Corporation (symbol: UTHR) was one of the worst losers
of the trading day today (2016-03-25), losing -10.47%. The number of shares
that changed hands was 1,928,372, or about 3 times the average daily volume
in the stock.
The closing price was $108.87, amounting to a market cap of $4,940,000,000,
about -42.79% off the highest price in the last 12 months. The stock has
been trading at a range between $107.51 and $190.29.
UTHR is in the Major Pharmaceuticals industry, part of the Health Care
sector. It first went public in 1999.
Looking at its valuation, the stock is now trading at 8.56 times earnings.