$AGIO is one of biggest losers #stocks today. read more:

Agios Pharmaceuticals, Inc. (symbol: AGIO) was one of the worst losers of
the trading day today (2015-10-05), losing -4.65%. The number of shares
that changed hands was 1,073,241, or about 2 times the average daily volume
in the stock.
The closing price was $72.55, amounting to a market cap of $2,720,000,000,
about -47.75% off the highest price in the last 12 months. The stock has
been trading at a range between $59.5 and $138.85.
AGIO is in the Major Pharmaceuticals industry, part of the Health Care
sector. It first went public in 2013.