$AGIO is one of biggest losers #stocks today. read more:

Agios Pharmaceuticals, Inc. (symbol: AGIO) was one of the worst losers of
the trading day today (2016-12-21), losing -6.37%. The number of shares
that changed hands was 1,011,198, or about 1 times the average daily volume
in the stock.
The closing price was $43.38, amounting to a market cap of $1,820,000,000,
about -36.19% off the highest price in the last 12 months. The stock has
been trading at a range between $33.5 and $67.98.
AGIO is in the Major Pharmaceuticals industry, part of the Health Care
sector. It first went public in 2013.