$ESRX is one of biggest losers #stocks today. read more:

Express Scripts Holding Company (symbol: ESRX) was one of the worst losers
of the trading day today (2016-08-25), losing -6.03%. The number of shares
that changed hands was 13,813,669, or about 4 times the average daily
volume in the stock.
The closing price was $71.74, amounting to a market cap of $45,210,000,000,
about -19.57% off the highest price in the last 12 months. The stock has
been trading at a range between $65.55 and $89.2.
ESRX is in the Medical/Nursing Services industry, part of the Health Care
sector. It first went public in 1992.
Looking at its valuation, the stock is now trading at 17.73 times earnings.