$APTO is one of biggest losers #stocks today. read more:

Aptose Biosciences, Inc. (symbol: APTO) was one of the worst losers of the
trading day today (2016-06-13), losing -7.09%. The number of shares that
changed hands was 104,182, or about 3 times the average daily volume in the
stock.
The closing price was $2.75, amounting to a market cap of $547,780,000,
about -57.03% off the highest price in the last 12 months. The stock has
been trading at a range between $1.93 and $6.4.
APTO is in the Biotechnology: Biological Products (No Diagnostic
Substances) industry, part of the Health Care sector.
Looking at its valuation, the stock is now trading at 80.88 times earnings.