$PCRX is one of biggest losers #stocks today. read more:

Pacira Pharmaceuticals, Inc. (symbol: PCRX) was one of the worst losers of
the trading day today (2015-09-24), losing -8.07%. The number of shares
that changed hands was 1,559,512, or about 2 times the average daily volume
in the stock.
The closing price was $51.47, amounting to a market cap of $1,890,000,000,
about -57.79% off the highest price in the last 12 months. The stock has
been trading at a range between $50.92 and $121.95.
PCRX is in the Major Pharmaceuticals industry, part of the Health Care
sector. It first went public in 2011.
Looking at its valuation, the stock is now trading at 481.03 times earnings.