$AGIO is one of biggest losers #stocks today. read more:

Agios Pharmaceuticals, Inc. (symbol: AGIO) was one of the worst losers of
the trading day today (2016-12-05), losing -12.45%. The number of shares
that changed hands was 3,544,226, or about 5 times the average daily volume
in the stock.
The closing price was $49.88, amounting to a market cap of $2,100,000,000,
about -26.63% off the highest price in the last 12 months. The stock has
been trading at a range between $33.5 and $67.98.
AGIO is in the Major Pharmaceuticals industry, part of the Health Care
sector. It first went public in 2013.