$AGIO is one of biggest losers #stocks today. read more:

Agios Pharmaceuticals, Inc. (symbol: AGIO) was one of the worst losers of
the trading day today (2016-01-06), losing -13.29%. The number of shares
that changed hands was 1,005,731, or about 1 times the average daily volume
in the stock.
The closing price was $55.87, amounting to a market cap of $2,100,000,000,
about -59.76% off the highest price in the last 12 months. The stock has
been trading at a range between $48.0 and $138.85.
AGIO is in the Major Pharmaceuticals industry, part of the Health Care
sector. It first went public in 2013.